Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601715 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL23387410 | 0.89 | ALOX15 (0.62) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL19765516 | 0.88 | ESR1 (0.42) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL23542367 | 0.87 | ALDH1A1 (0.59) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL1501375 | 0.83 | ALOX15 (0.54) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL27371451 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL19765498 | 0.82 | KDM4E (0.37) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL26607215 | 0.81 | CNR1 (0.35) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL12572591 | 0.80 | ALOX15 (0.48) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL27117241 | 0.80 | PGK1 (0.38) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016190871-A1 | 2,5-DIALKYL-4-H/HALO/ETHER-PHENOL COMPOUNDS | TANSNA THERAPEUTICS, INC. (US) | 2016-12-01 | — | — | WO | disclosed |