Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139811 | 0.86 | LCK (0.67) | IAPPALDH1A1LCKGAAPKM | |
| SCHEMBL18273962 | 0.86 | ERCC1 (0.49) | IAPPHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL14114460 | 0.85 | LCK (0.53) | HSD17B10KDM4EHIF1AALDH1A1HPGD | |
| SCHEMBL15976062 | 0.82 | LCK (0.51) | IAPPHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL12994075 | 0.81 | LCK (0.48) | HSD17B10KDM4EHIF1AALDH1A1HPGD | |
| SCHEMBL5370187 | 0.81 | NAALAD2 (0.54) | MAPTERCC1ERCC4GAACA1 | |
| SCHEMBL7709347 | 0.81 | NAALAD2 (0.54) | MAPTERCC1ERCC4GAACA1 | |
| SCHEMBL28794655 | 0.81 | CA1 (0.53) | HSD17B10KDM4EHIF1APTGS1MAPT | |
| SCHEMBL863196 | 0.80 | ALOX15 (0.54) | IAPPHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL12135794 | 0.80 | ALOX15 (0.54) | IAPPHSD17B10KDM4EHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160346424-A1 | ADHESIVE COMPOUNDS AND METHODS USE FOR HERNIA REPAIR | KNC NER ACQUISITION SUB, INC. | 2016-12-01 | — | — | US | disclosed |