Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.43 |
| ▸ | LPL | P06858 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823266 | 0.92 | LIPG (0.48) | LIPGLPLALDH1A1TP53TDP1 | |
| SCHEMBL5892478 | 0.82 | LIPG (0.53) | LIPGLPLALDH1A1IRAK4 | |
| SCHEMBL30435177 | 0.77 | — | — | |
| SCHEMBL50668 | 0.77 | — | — | |
| SCHEMBL31390229 | 0.76 | LIPG (0.48) | LIPGLPLALDH1A1P4HBIRAK4 | |
| SCHEMBL8020207 | 0.76 | LIPG (0.48) | LIPGLPLALDH1A1P4HBIRAK4 | |
| SCHEMBL18479991 | 0.76 | LIPG (0.48) | LIPGLPLP4HBIRAK4 | |
| SCHEMBL26071363 | 0.76 | LIPG (0.44) | LIPGLPLP4HB | |
| SCHEMBL15372954 | 0.75 | LIPG (0.47) | LIPGLPLP4HBIRAK4 | |
| SCHEMBL8715895 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TP53TDP1MAPTHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324032-A2 | INHIBITORS OF BETA-SECRETASE | Vitae Pharmaceuticals, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |