Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50668 | 0.98 | — | — | |
| SCHEMBL30435177 | 0.98 | — | — | |
| Ethylene Glycol SCHEMBL5831465 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1TP53HSD17B3TSHR | |
| SCHEMBL1983389 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1TP53HSD17B3TSHR | |
| Methyl Alcohol SCHEMBL27537082 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1TP53HSD17B3HSD11B1 | |
| SCHEMBL31539537 | 0.82 | — | — | |
| SCHEMBL10446773 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TDP1TP53HSD17B3HSD11B1 | |
| Vinyl Ether SCHEMBL5832123 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1TP53HSD17B3TSHR | |
| Glycine SCHEMBL30864261 | 0.80 | HSD17B3 (0.49) | ALDH1A1TDP1HSD17B3MAPTNPSR1 | |
| SCHEMBL21881 | 0.79 | TDP1 (0.67) | ALDH1A1TDP1TP53TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63230647-A | — | — | None | — | — | JP | disclosed |
| CN-114985002-B | Biphosphine polymer catalyst for olefin hydroformylation, preparation method and application thereof | 中海油天津化工研究设计院有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114874082-B | Method for preparing high-carbon aldehyde by hydroformylation of mixed alpha olefin | 中海油天津化工研究设计院有限公司 | 2023-08-04 | — | — | CN | disclosed |
| EP-0722448-A4 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO INC (US) | 1998-04-29 | — | — | EP | disclosed |
| US-5693648-A | TREATMENT OF AUTOIMMUNE DISEASES, INFECTIOUS DISEASES, PREVENTING REJECTION OF ORGAN TRANSPLANTS | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5565560-A | TREATING AUTOIMMUNE DISEASES, PREVENTING TRANSPLANT REJECTION | MERCK & CO., INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0722448-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO. INC. (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5532248-A | O-aryl,O-alkyl, and O-alkenyl-macrolides having immunosuppressive activity | MERCK CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |
| WO-1995009857-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |
| US-5250678-A | For autoimmune, infectious diseases, organ transplant rejection; skin diseases, antiinflammatory agents | MERCK & CO., INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0515071-A2 | O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity | MERCK & CO. INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| JP-S63230647-A | (3-VINYLPHENYL)PHENYLMETHANE | NIPPON PETROCHEM CO LTD | 1988-09-27 | — | — | JP | disclosed |
| EP-0282063-A1 | 1-(3-Vinylphenyl)-1-phenyl-hydrocarbons and method for producing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282065-A2 | (Phenylethenyl) phenylpropionic acid and its ester, and method for producing (benzoylphenyl) propionic acid or its ester | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |