SCHEMBL1827472

SCHEMBL1827472

CC1(C)OB(c2ccc(-c3ccccn3)cc2)OC1(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 12/20 0.62
LPL P06858 11/20 0.62
DGAT1 O75907 1/20 0.52
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
P4HB P07237 1/20 0.43
CYP2A6 P11509 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
CCR1 P32246 1/20 0.41
CCR5 P51681 1/20 0.41
CCR8 P51685 1/20 0.41
METAP1 P53582 1/20 0.41
BLM P54132 1/20 0.41
HIF1A Q16665 1/20 0.41
DOHH Q9BU89 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413172 1.00 LIPG (0.62) LIPGLPLDGAT1CYP1A2CYP2D6
SCHEMBL23624669 0.90 LIPG (0.59) LIPGLPLDGAT1P4HBCYP2A6
SCHEMBL21416108 0.90 LIPG (0.51) LIPGLPLDGAT1CYP1A2CYP2D6
SCHEMBL19106600 0.89 LIPG (0.61) LIPGLPLDGAT1P4HBCYP2A6
SCHEMBL19106491 0.88 LIPG (0.51) LIPGLPLDGAT1CYP1A2CYP2D6
SCHEMBL19106593 0.87 LPL (0.54) LIPGLPLDGAT1P4HBKDM4E
SCHEMBL24475241 0.86 LPL (0.50) LIPGLPLDGAT1P4HBKDM4E
SCHEMBL22222507 0.86 LIPG (0.47) LIPGLPLDGAT1CYP1A2CYP2D6
SCHEMBL19544227 0.86 LPL (0.47) LIPGLPLDGAT1CYP1A2CYP2D6
SCHEMBL23033871 0.86 LIPG (0.56) LIPGLPLDGAT1CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3483153-B1 COMPOUNDS COMPRISING TRIAZINE GROUP, FLUORENE-GROUP AND ARYL GROUP AND THEIR USE IN ORGANIC ELECTRONIC DEVICES NOVALED GMBH (DE) 2026-04-29 EP disclosed
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2025-03-27 US disclosed
US-12139479-B2 Heterocycle substituted pyridine derivative antifungal agents BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) 2024-11-12 US disclosed
EP-3529250-B1 IMIDAZOPYRAZINONES, PYRAZOLOPYRIMIDINONES AND PYRAZOLOPYRIDINONES AS PDE1 INHIBITORS H LUNDBECK AS (DK) 2023-12-06 EP disclosed
CN-116987124-A Metal complexes as luminophores in organic electroluminescent devices 默克专利有限公司 2023-11-03 CN disclosed
EP-3720438-B1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS AMPLYX PHARMACEUTICALS INC (US) 2023-08-30 EP disclosed
US-20230065881-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS AMPLYX PHARMACEUTICALS, INC. (US) 2023-03-02 US disclosed
US-11512079-B2 Heterocycle substituted pyridine derivative antifungal agents AMPLYX PHARMACEUTICALS, INC. (US) 2022-11-29 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
CN-109843884-B Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as PDE1 inhibitors H.隆德贝克有限公司 2022-03-04 CN disclosed
WO-2011068204-A1 BENZO[C]CARBAZOLE COMPOUND THAT HAS SUBSTITUENT BEARING PYRIDINE RING, AND ORGANIC ELECTROLUMINESCENT ELEMENT JNC株式会社 (JP) 2011-06-09 WO disclosed
EP-2315753-A2 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME Cheil Industries Inc. (KR) 2011-05-04 EP disclosed
US-20100276673-A1 Organic compound, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-11-04 US disclosed
WO-2010074422-A1 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2010-07-01 WO disclosed
US-20100127215-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS BASF SE (DE) 2010-05-27 US disclosed
US-20100109515-A1 OLED WITH METAL COMPLEXES HAVING A HIGH QUANTUM EFFICIENCY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-05-06 US disclosed
WO-2010024572-A2 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2010-03-04 WO disclosed
WO-2010024572-A2 MATERIAL FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES INC. (KR) 2010-03-04 WO disclosed
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-14 US disclosed
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101012-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS ERG28, DPM1, CYP51A1 LIPG 4496/4885LPL 4735/4885DGAT1 4070/4885
US-20230065881-A1 HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVE ANTIFUNGAL AGENTS ERG28, DPM1, CYP51A1 LIPG 4496/4885LPL 4735/4885DGAT1 4070/4885
US-12139479-B2 Heterocycle substituted pyridine derivative antifungal agents ERG28, DPM1, CYP51A1 LIPG 4496/4885LPL 4735/4885DGAT1 4070/4885
US-11512079-B2 Heterocycle substituted pyridine derivative antifungal agents ERG28, DPM1, CYP51A1 LIPG 4496/4885LPL 4735/4885DGAT1 4070/4885
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES BMI1, PCNA, DNMT1 LIPG 4740/4885LPL 4439/4885DGAT1 4580/4885
US-20100127215-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS OCIAD1, ORC3, OCIAD2 LIPG 2896/4885LPL 3087/4885DGAT1 600/4885
US-20100276673-A1 Organic compound, and organic photoelectric device including the same OR10J3, EPB41, CACNA2D4 LIPG 4642/4885LPL 3981/4885DGAT1 1679/4885
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 LIPG 4256/4885LPL 4368/4885DGAT1 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.