SCHEMBL18280265

SCHEMBL18280265

C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](OS(=O)(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.77
ABCC4 O15439 2/20 0.77
GPBAR1 Q8TDU6 9/20 0.72
NR1H4 Q96RI1 4/20 0.72
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
ABCB11 O95342 2/20 0.72
SLC10A2 Q12908 2/20 0.72
SLC10A1 Q14973 2/20 0.72
LMNA P02545 1/20 0.72
CYP2C19 P33261 1/20 0.72
CHRM2 P08172 1/20 0.72
ADRA2A P08913 1/20 0.72
ADRA1A P35348 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
ENPP2 Q13822 1/20 0.72
CISD1 Q9NZ45 1/20 0.72
CYP3A4 P08684 1/20 0.72
ABCC1 P33527 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18280267 1.00 VDR (0.77) VDRABCC4GPBAR1NR1H4MEN1
SCHEMBL1654530 1.00 VDR (0.77) VDRABCC4GPBAR1NR1H4MEN1
SCHEMBL28901763 1.00 VDR (0.77) VDRABCC4GPBAR1NR1H4MEN1
SCHEMBL1655224 1.00 VDR (0.77) VDRABCC4GPBAR1NR1H4MEN1
SCHEMBL19360936 0.93 VDR (0.77) VDRABCC4GPBAR1NR1H4MEN1
Ursulcholic Acid SCHEMBL5683101 0.92 GPBAR1 (0.72) VDRABCC4GPBAR1NR1H4MEN1
Ursulcholic Acid SCHEMBL27095060 0.91 ABCC4 (0.77) VDRABCC4GPBAR1NR1H4MEN1
Ursulcholic Acid SCHEMBL2919469 0.91 ABCC4 (0.77) VDRABCC4GPBAR1NR1H4MEN1
Ursulcholic Acid SCHEMBL6269998 0.91 ABCC4 (0.77) VDRABCC4GPBAR1NR1H4MEN1
SCHEMBL232879 0.91 ABCC4 (0.79) VDRABCC4GPBAR1NR1H4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4259099-A1 BIOLOGICAL DELIVERY SYSTEMS Particella, Inc. (US) 2023-10-18 EP claimed
WO-2022132678-A1 BIOLOGICAL DELIVERY SYSTEMS DNALITE THERAPEUTICS, INC. (US) 2022-06-23 WO claimed
US-11247904-B2 Scroll composite having amphiphilic substance inside and method for preparation of the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-02-15 US claimed
US-20160355401-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2016-12-08 US claimed
EP-4259099-A1 BIOLOGICAL DELIVERY SYSTEMS Particella, Inc. (US) 2023-10-18 EP disclosed
WO-2022132678-A1 BIOLOGICAL DELIVERY SYSTEMS DNALITE THERAPEUTICS, INC. (US) 2022-06-23 WO disclosed
US-11247904-B2 Scroll composite having amphiphilic substance inside and method for preparation of the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-02-15 US disclosed
US-11247904-B2 Scroll composite having amphiphilic substance inside and method for preparation of the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-02-15 US disclosed
US-20200165136-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2020-05-28 US disclosed
US-20160355401-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2016-12-08 US disclosed
US-20160355401-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2016-12-08 US disclosed
US-20160355401-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2016-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165136-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME PSAP, SGMS2, SDCBP VDR 2071/4885ABCC4 1831/4885GPBAR1 3346/4885
US-20160355401-A1 SCROLL COMPOSITE HAVING AMPHIPHILIC SUBSTANCE INSIDE AND METHOD FOR PREPARATION OF THE SAME PSAP, SGMS2, SDCBP VDR 2071/4885ABCC4 1831/4885GPBAR1 3346/4885
US-11247904-B2 Scroll composite having amphiphilic substance inside and method for preparation of the same PSAP, SGMS2, SDCBP VDR 2071/4885ABCC4 1831/4885GPBAR1 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.