SCHEMBL18280692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2628369	0.79	KIF11 (0.58)	KIF11MAPTCHEK1METAP2AURKA
	SCHEMBL29539315	0.77	KIF11 (0.81)	KIF11MAPT
	SCHEMBL2606005	0.77	KIF11 (0.81)	KIF11MAPT
	SCHEMBL10312973	0.76	KIF11 (1.00)	KIF11CHEK1AURKAPLK4CHUK
	SCHEMBL29362207	0.76	KIF11 (1.00)	KIF11CHEK1AURKAPLK4CHUK
	SCHEMBL23319573	0.76	MAPT (0.49)	MAPTCHEK1AURKAPARP1CHUK
	SCHEMBL21070513	0.76	MAPT (0.49)	MAPTCHEK1AURKAPARP1PDK2
	SCHEMBL1586081	0.76	MAPT (0.49)	MAPTCHEK1AURKAPARP1MEN1
	SCHEMBL1181804	0.76	MAPT (0.49)	KIF11MAPTCHEK1METAP2AURKA
	Bromide SCHEMBL30567841	0.75	KIF11 (0.78)	KIF11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.