SCHEMBL182808

SCHEMBL182808

CC1(O)C(O)=C(C(=O)O)N(Cc2ccccc2)C1(C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
AMPD2 Q01433 6/20 0.42
ELANE P08246 1/20 0.38
NOTUM Q6P988 2/20 0.37
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
POLB P06746 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GRM6 O15303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858443 0.75 ALDH1A1 (0.37) ALDH1A1AMPD2ELANENOTUMLMNA
SCHEMBL6049149 0.74 ALDH1A1 (0.50) ALDH1A1AMPD2ELANELMNATSHR
SCHEMBL24478723 0.66 ALDH1A1 (0.51) ALDH1A1AMPD2ELANEGAA
SCHEMBL10668347 0.66 AMPD2 (0.43) ALDH1A1AMPD2ELANELMNATSHR
SCHEMBL8876707 0.65 ALDH1A1 (0.50) ALDH1A1AMPD2ELANETSHRGAA
SCHEMBL10948588 0.63 ELANE (0.48) ALDH1A1AMPD2ELANEGAA
SCHEMBL23608654 0.63 ELANE (0.63) ALDH1A1ELANESMN1; SMN2GAA
SCHEMBL23608653 0.63 GAA (0.43) AMPD2ELANENOTUMTSHRGAA
SCHEMBL289493 0.63 AMPD2 (0.46) ALDH1A1AMPD2ELANELMNAGAA
SCHEMBL3733166 0.63 TSHR (0.52) ALDH1A1AMPD2ELANELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465962-B1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIV FLORIDA (US) 2012-01-04 EP disclosed
EP-1465962-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2004-10-13 EP disclosed
US-6791738-B2 CONTROLLING COLOR, BRIGHTNESS AND ENVIRONMENTAL STABILITY; POLY- 3,4-ALKYLENEDIOXYHETEROCYCLES UNIVERSITY OF FLORIDA 2004-09-14 US disclosed
US-20030174377-A1 Electrochromic polymers and polymer electrochromic devices UNIVERSITY OF FLORIDA 2003-09-18 US disclosed
WO-2003046106-A1 ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES UNIVERSITY OF FLORIDA (US) 2003-06-05 WO disclosed