SCHEMBL1828409

SCHEMBL1828409

OC1(C=Cc2ccccc2)C=CC=CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.34
HDAC4 P56524 3/20 0.33
LMNA P02545 3/20 0.33
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
PLIN1 O60240 2/20 0.33
MAPT P10636 2/20 0.33
RECQL P46063 2/20 0.33
PLIN5 Q00G26 2/20 0.33
ABHD5 Q8WTS1 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TNKS O95271 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28136076 0.82 MAOB (0.37) MAOBHDAC4LMNAHDAC3HDAC1
SCHEMBL8742114 0.77 MAOB (0.35) MAOBHDAC4LMNAHDAC3HDAC1
SCHEMBL28343173 0.76 MAOB (0.34) MAOBLMNAALDH1A1TRPA1CHAT
SCHEMBL3423749 0.74 MAPT (0.41) MAOBHDAC4LMNAHDAC3HDAC1
Bromide SCHEMBL28167446 0.73 MAOB (0.32) MAOBHDAC4CHAT
SCHEMBL28766223 0.73 CYP3A4 (0.35) CHATGLATDP1
SCHEMBL7781550 0.73 MAOB (0.38) MAOBHDAC4LMNAHDAC3HDAC1
SCHEMBL22572818 0.71 MAPT (0.44) MAOBHDAC4LMNAHDAC3HDAC1
SCHEMBL3414986 0.70
SCHEMBL7965919 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2315583-B1 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2018-05-09 EP claimed
EP-2238967-B1 Skin treatment fighting skin aging II HENKEL AG & CO KGAA (DE) 2018-05-02 EP claimed
EP-2964333-A1 POWDERED COMPOSITION FOR USE IN THE PREPARATION OF WHITENING COSMETIC COMPOSITIONS Sensient Cosmetic Technologies (FR) 2016-01-13 EP claimed
WO-2014135497-A1 POWDERED COMPOSITION FOR USE IN THE PREPARATION OF WHITENING COSMETIC COMPOSITIONS SENSIENT COSMETIC TECHNOLOGIES (FR) 2014-09-12 WO claimed
JP-2011528336-A 2011-11-17 JP claimed
EP-2315583-A2 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE Yvery (FR) 2011-05-04 EP claimed
EP-1845957-B1 METHOD FOR PRODUCING A DRUG EXTRACT THAT CONTAINS HYDROXYSTILBENES HEGER PETER (DE) 2010-12-22 EP claimed
WO-2010007252-A2 FORMULATION FOR IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE YVERY (FR) 2010-01-21 WO claimed
EP-1068864-B1 Use of at least one hydroxystilbene as glycation inhibitor OREAL (FR) 2005-02-09 EP claimed
EP-1064931-B1 Cosmetic composition containing at least one hydroxystilbene and ascorbic acid OREAL (FR) 2004-12-15 EP claimed
EP-0953344-B1 Use of at least a hydroxystilbene in a composition to stimulate desquamation of the skin. OREAL (FR) 2004-05-26 EP claimed
EP-0953345-B1 Use of at least a hydroxystilbene as an agent for decreasing micro-organisms adhesion OREAL (FR) 2004-04-28 EP claimed
EP-0953346-B1 Use of at least a hydroxystilbene in a skin fortifying composition OREAL (FR) 2003-11-26 EP claimed
EP-1234571-A1 Topical composition containing a hydroxystilbene and a polyol L'OREAL (FR) 2002-08-28 EP claimed
EP-1175888-A2 Topical compositions comprising glycosylated hydroxystilbenes and their uses L'OREAL (FR) 2002-01-30 EP claimed
EP-1068864-A1 Use of at least a hydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-01-17 EP claimed
EP-1064931-A1 Cosmetic composition containing at least an hydroxystilbene and ascorbic acid L'OREAL (FR) 2001-01-03 EP claimed
EP-0953346-A1 Use of at least a hydroxystilbebe in a skin fortifying composition L'OREAL (FR) 1999-11-03 EP claimed
EP-0953345-A1 Use of at least a hydroxystilbene as an agent for decreasing micro-organism adhesion L'OREAL (FR) 1999-11-03 EP claimed
EP-0953344-A1 Use of at least one hydroxystilbene in a composition to stimulate desquamation of the skin and compositions containing it L'OREAL (FR) 1999-11-03 EP claimed