Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.69 |
| ▸ | CA1 | P00915 | 11/20 | 0.69 |
| ▸ | CA9 | Q16790 | 11/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.68 |
| ▸ | CA7 | P43166 | 6/20 | 0.66 |
| ▸ | CA6 | P23280 | 5/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.66 |
| ▸ | CA4 | P22748 | 5/20 | 0.66 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.66 |
| ▸ | CA5A | P35218 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA3 | P07451 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (E)-7-(2-Butenyloxy)Coumarin SCHEMBL12189889 | 1.00 | CA12 (0.69) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL12189883 | 0.87 | CA12 (0.68) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL12189878 | 0.84 | CA12 (0.68) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL12189886 | 0.84 | CA12 (0.68) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL4390495 | 0.83 | CA12 (0.75) | CA12CA1CA9KDM4EMTNR1A | |
| 7-Allyloxycoumarin SCHEMBL4765530 | 0.82 | CA12 (1.00) | CA12CA1CA9KDM4EMTNR1A | |
| 7-Prenyloxycoumarin SCHEMBL4898255 | 0.81 | KDM4E (1.00) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL18292781 | 0.81 | MTNR1A (0.67) | CA12CA1CA9KDM4EMTNR1A | |
| Ethoxycoumarin SCHEMBL119072 | 0.80 | CA9 (1.00) | CA12CA1CA9KDM4EMTNR1A | |
| SCHEMBL12304245 | 0.79 | CA12 (0.81) | CA12CA1CA9KDM4EMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |