Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | NDUFS8 | O00217 | 3/20 | 0.79 |
| ▸ | COXFA4 | O00483 | 3/20 | 0.79 |
| ▸ | NDUFAB1 | O14561 | 3/20 | 0.79 |
| ▸ | NDUFA1 | O15239 | 3/20 | 0.79 |
| ▸ | NDUFS4 | O43181 | 3/20 | 0.79 |
| ▸ | NDUFB5 | O43674 | 3/20 | 0.79 |
| ▸ | NDUFB3 | O43676 | 3/20 | 0.79 |
| ▸ | NDUFC1 | O43677 | 3/20 | 0.79 |
| ▸ | NDUFA2 | O43678 | 3/20 | 0.79 |
| ▸ | NDUFS5 | O43920 | 3/20 | 0.79 |
| ▸ | NDUFS7 | O75251 | 3/20 | 0.79 |
| ▸ | NDUFS2 | O75306 | 3/20 | 0.79 |
| ▸ | NDUFS6 | O75380 | 3/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898116 | 0.90 | KDM4E (0.82) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| Auraptene SCHEMBL2535034 | 0.89 | ALOX15 (1.00) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| Auraptene SCHEMBL2535029 | 0.89 | ALOX15 (1.00) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| SCHEMBL18265492 | 0.88 | KDM4E (0.78) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| Umbelliprenin SCHEMBL26641528 | 0.88 | ALOX15 (1.00) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| Umbelliprenin SCHEMBL18265478 | 0.88 | ALOX15 (1.00) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| Umbelliprenin SCHEMBL28133292 | 0.88 | ALOX15 (1.00) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| SCHEMBL29999425 | 0.83 | NDUFS8 (0.83) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| SCHEMBL24700226 | 0.82 | NDUFS8 (0.81) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 | |
| SCHEMBL4390495 | 0.82 | CA12 (0.75) | KDM4EALDH1A1MTNR1AALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |
| US-8729279-B2 | Agent for promoting osteoblast differentiation, pharmaceutical composition for promoting bone formation, and food for special dietary use containing auraptene analog as active ingredient | ERINA CO., INC. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-8729279-B2 | Agent for promoting osteoblast differentiation, pharmaceutical composition for promoting bone formation, and food for special dietary use containing auraptene analog as active ingredient | ERINA CO., INC. (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2001463-B1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2013-07-03 | — | — | EP | disclosed |
| US-20130102796-A1 | AGENT FOR PROMOTING OSTEOBLAST DIFFERENTIATION, PHARMACEUTICAL COMPOSITION FOR PROMOTING BONE FORMATION, AND FOOD FOR SPECIAL DIETARY USE CONTAINING AURAPTENE ANALOG AS ACTIVE INGREDIENT | ERINA CO., INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20130102796-A1 | AGENT FOR PROMOTING OSTEOBLAST DIFFERENTIATION, PHARMACEUTICAL COMPOSITION FOR PROMOTING BONE FORMATION, AND FOOD FOR SPECIAL DIETARY USE CONTAINING AURAPTENE ANALOG AS ACTIVE INGREDIENT | ERINA CO., INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20120277297-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-11-01 | — | — | US | disclosed |
| US-8188143-B2 | Pharmaceutical composition useful as acetylcholinesterase inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-05-29 | — | — | US | disclosed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | disclosed |
| WO-2003028762-A1 | NOVEL ANTIMICROBIAL RESISTANCE BLOCKING COMPOSITIONS | ETHICON, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | ACHE, BCHE, CHRNB1 | KDM4E 1482/4885ALDH1A1 1025/4885MTNR1A 302/4885 |
| US-20130102796-A1 | AGENT FOR PROMOTING OSTEOBLAST DIFFERENTIATION, PHARMACEUTICAL COMPOSITION FOR PROMOTING BONE FORMATION, AND FOOD FOR SPECIAL DIETARY USE CONTAINING AURAPTENE ANALOG AS ACTIVE INGREDIENT | MYADM, EBP, HGFAC | KDM4E 573/4885ALDH1A1 368/4885MTNR1A 390/4885 |
| US-20120277297-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | ACHE, BCHE, CYP3A7 | KDM4E 1461/4885ALDH1A1 547/4885MTNR1A 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.