Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211507 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL18285008 | 0.99 | KDM4E (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL20211549 | 0.89 | ALOX5 (0.36) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL20211550 | 0.89 | ALOX5 (0.36) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6809240 | 0.87 | CA2 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27536297 | 0.87 | CA2 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL18285162 | 0.87 | CA2 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6809242 | 0.87 | CA2 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29884782 | 0.81 | PSMB2 (0.44) | CA2 | |
| SCHEMBL29886327 | 0.81 | PSMB2 (0.44) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793609-B2 | Compressed pathways for nonribosomal molecular biosynthesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-06 | — | — | US | claimed |
| US-20180155400-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-07 | — | — | US | claimed |
| WO-2016196940-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-08 | — | — | WO | claimed |
| US-10793609-B2 | Compressed pathways for nonribosomal molecular biosynthesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-06 | — | — | US | disclosed |
| US-10793609-B2 | Compressed pathways for nonribosomal molecular biosynthesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180155400-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180155400-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180155400-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-07 | — | — | US | disclosed |
| WO-2016196940-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155400-A1 | COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS | VGF, COASY, VIP | KDM4E 1909/4885ALDH1A1 4662/4885LMNA 2469/4885 |
| US-10793609-B2 | Compressed pathways for nonribosomal molecular biosynthesis | VGF, COASY, VIP | KDM4E 1909/4885ALDH1A1 4662/4885LMNA 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.