Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18286378 | 0.92 | MEN1 (0.31) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14825137 | 0.91 | MEN1 (0.32) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18286382 | 0.87 | RARB (0.38) | MAPTMEN1ALDH1A1KMT2AS1PR1 | |
| SCHEMBL13049488 | 0.86 | ALDH1A1 (0.36) | MAPTMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14981805 | 0.86 | ALDH1A1 (0.38) | HSD17B1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11966928 | 0.84 | ALDH1A1 (0.40) | HSD17B1HSD17B2MAPTMEN1ALDH1A1 | |
| SCHEMBL18286390 | 0.84 | ESR2 (0.44) | HSD17B1HSD17B2MAPTMEN1ALDH1A1 | |
| SCHEMBL13921998 | 0.83 | ESR2 (0.33) | HSD17B1MAPTMEN1KMT2AESR1 | |
| SCHEMBL13049537 | 0.83 | HSD17B1 (0.35) | HSD17B1HSD17B2MAPTMEN1ALDH1A1 | |
| SCHEMBL11966921 | 0.82 | ESR2 (0.39) | HSD17B1MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9515267-B2 | Electroactive materials | EI DU PONT DE NEMOURS AND COMPANY (US) | 2016-12-06 | — | — | US | disclosed |