SCHEMBL13049488

SCHEMBL13049488

Cc1ccc(-c2cc(C)c(-c3ccc(N(c4ccc(-c5c(C)cc(C)cc5C)cc4)c4ccc(-c5c(C)cc(C)cc5C)cc4)cc3)cc2C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
RAPGEF4 Q8WZA2 2/20 0.32
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
USP7 Q93009 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11966928 0.91 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13921982 0.89 CRHR1 (0.32) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL14825137 0.89 MEN1 (0.32) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13049486 0.87 ALDH1A1 (0.35) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL18286378 0.87 MEN1 (0.31) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL18286368 0.86 HSD17B1 (0.33) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13049487 0.82 MAPT (0.36) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11966921 0.82 ESR2 (0.39) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13049531 0.82 MEN1 (0.33) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL16386572 0.81 HPRT1 (0.45) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1464691-B1 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS INC (JP) 2013-10-02 EP disclosed
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 US disclosed
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 US disclosed
US-7485376-B2 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-03 US disclosed
US-7485376-B2 Organic electroluminescent element, illuminator, and display KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-03 US disclosed