Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 12/20 | 0.53 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752851 | 0.92 | RXFP1 (0.54) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12606017 | 0.85 | RXFP1 (0.67) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL1774875 | 0.84 | RXFP1 (0.70) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL13929951 | 0.83 | RXFP1 (0.64) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL13929953 | 0.77 | RXFP1 (0.62) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL13754010 | 0.76 | RXFP1 (0.73) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL1775112 | 0.76 | RXFP1 (0.65) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL14192649 | 0.75 | RXFP1 (0.66) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12606012 | 0.75 | SIRT2 (0.53) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL9268782 | 0.75 | RXFP1 (0.78) | RXFP1YAP1TEAD4TEAD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940841-B9 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-1940841-B1 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2016-12-07 | — | — | EP | disclosed |