Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404107 | 0.96 | ALOX15 (0.38) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL895686 | 0.80 | TSHR (0.39) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL6863765 | 0.79 | TDP1 (0.40) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL5310540 | 0.79 | ALOX15 (0.50) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL29000852 | 0.79 | ALOX15 (0.50) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL581924 | 0.79 | ALOX15 (0.50) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| Ammonia Solution, Strong SCHEMBL18140150 | 0.78 | TSHR (0.38) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| Hydrochloric Acid SCHEMBL10892024 | 0.77 | ALOX15 (0.48) | ALOX15TDP1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL26103782 | 0.75 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL1361863 | 0.74 | TDP1 (0.33) | TDP1SMN1; SMN2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140234410-A1 | COMBINATION PRODUCTS | SIGMOID PHARMA LTD. (IE) | 2014-08-21 | — | — | US | disclosed |
| EP-2322146-B1 | Microcapsule formulations comprising two pharmaceutically active ingredients | SIGMOID PHARMA LTD (IE) | 2012-12-12 | — | — | EP | disclosed |
| EP-2444071-A1 | Minicapsule formulations | Sigmoid Pharma Limited (IE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2322146-A2 | Microcapsule formulations comprising two pharmaceutically active ingredients | Sigmoid Pharma Limited (IE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2156826-A1 | Microcapsule formulations comprising two pharmaceutically active ingredients | Sigmoid Pharma Limited (IE) | 2010-02-24 | — | — | EP | disclosed |
| EP-2153824-A1 | Seamless multiparticulate formulations | Sigmoid Pharma Limited (IE) | 2010-02-17 | — | — | EP | disclosed |
| US-20080113031-A1 | seamless capsules having cores containing drugs, to enhance bioavailability, sustained release or time release of drugs | SIGMOID PHARMA LIMITED (IE) | 2008-05-15 | — | — | US | disclosed |
| US-20080020018-A1 | Combination Products | SIGMOID PHARMA LIMITED (IE) | 2008-01-24 | — | — | US | disclosed |
| EP-1811979-A2 | MICROCAPSULES COMPRISING A METHYLXANTHINE AND A CORTICOSTEROID | Sigmoid Biotechnologies Limited (IE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1802287-A2 | MINICAPSULE FORMULATIONS | Sigmoid Biotechnologies Limited (IE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006035418-A2 | MICROCAPSULES COMPRISING A METHYLXANTHINE AND A CORTICOSTEROID | SIGMOID BIOTECHNOLOGIES LIMITED (IE) | 2006-04-06 | — | — | WO | disclosed |
| WO-2006035416-A2 | MINICAPSULE FORMULATIONS | SIGMOID BIOTECHNOLOGIES LIMITED (IE) | 2006-04-06 | — | — | WO | disclosed |