Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404107 | 0.82 | ALOX15 (0.38) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL2048611 | 0.80 | TDP1 (0.36) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL8812874 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL6008457 | 0.79 | EGLN1 (0.39) | TDP1SMN1; SMN2SLC22A6FOLH1LMNA | |
| SCHEMBL1828772 | 0.79 | ALOX15 (0.36) | TDP1SMN1; SMN2SLC22A6ALOX15LMNA | |
| SCHEMBL895686 | 0.79 | TSHR (0.39) | TDP1SMN1; SMN2SLC22A6ALOX15LMNA | |
| Bicarbonate SCHEMBL6393528 | 0.78 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1ALOX15 | |
| SCHEMBL11094949 | 0.77 | ALOX15 (0.35) | TDP1SMN1; SMN2SLC22A6ALOX15 | |
| SCHEMBL1361863 | 0.77 | TDP1 (0.33) | TDP1SMN1; SMN2SLC22A6 | |
| Ammonia Solution, Strong SCHEMBL18140150 | 0.77 | TSHR (0.38) | TDP1SMN1; SMN2SLC22A6ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800218-B2 | Abrasive free formulations for chemical mechanical polishing of copper and associated materials and method of using same | ADVANCED TECHNOLOGY MATERIALS, INC. | 2004-10-05 | — | — | US | claimed |
| US-5980924-A | IMPREGNATED SHEET WITH AN AQUEOUS COMPOSITION CONTAINING A NONIONIC SURFACTANT AND A POLYHYDRIC ALCOHOL OR GLYCOL ETHER; TO SMEAR AND REMOVE MAKEUP AND SEBUM, LOW IRRITATIVENESS TO THE SKIN | KAO CORPORATION (JP) | 1999-11-09 | — | — | US | claimed |
| US-4026711-A | TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM PHOSPHATE-CARBOXYLATE, UREA | AMERICAN CYANAMID COMPANY (US) | 1977-05-31 | — | — | US | claimed |