Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187731 | 1.00 | SIGMAR1 (0.49) | SIGMAR1MEN1KMT2AHTR2ARELA | |
| SCHEMBL1058150 | 0.88 | SIGMAR1 (0.46) | SIGMAR1MEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL11496622 | 0.88 | MEN1 (0.53) | SIGMAR1MEN1KMT2AHTR2ARELA | |
| SCHEMBL33528489 | 0.86 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL11385636 | 0.84 | FLT3 (0.38) | SIGMAR1MEN1KMT2AHTR2ARELA | |
| SCHEMBL11440056 | 0.84 | LTA4H (0.54) | MEN1KMT2ARELALMNAKDM4E | |
| SCHEMBL4595058 | 0.84 | SIGMAR1 (0.46) | SIGMAR1MEN1KMT2AHTR2ARELA | |
| SCHEMBL1829150 | 0.80 | MEN1 (0.49) | SIGMAR1MEN1KMT2AHTR2AKCNH2 | |
| SCHEMBL11135424 | 0.80 | APP (0.50) | — | |
| SCHEMBL11135426 | 0.80 | APP (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399594-B2 | Blocked-isocyanate silicone resins | DOW CORNING CORPORATION (US) | 2013-03-19 | — | — | US | disclosed |
| EP-2102286-B1 | BLOCKED ISOCYANATE SILICONE RESINS | DOW CORNING (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20100093902-A1 | Blocked-Isocyanate Silicone Resins | DOW CORNING CORPORATION | 2010-04-15 | — | — | US | disclosed |
| EP-2102286-A1 | BLOCKED ISOCYANATE SILICONE RESINS | Dow Corning Corporation (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008088492-A1 | BLOCKED ISOCYANATE SILICONE RESINS | DOW CORNING CORPORATRION (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20070167587-A1 | Process for producing polymer with functional end | KURARAY CO., LTD. (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1721912-A1 | PROCESS FOR PRODUCING POLYMER WITH FUNCTIONAL END | KURARAY CO., LTD. (JP) | 2006-11-15 | — | — | EP | disclosed |