Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828829 | 1.00 | ESR1 (0.49) | ESR1ESR2FOLH1KDM6BCA2 | |
| SCHEMBL24489505 | 0.86 | KDM6B (0.47) | ESR1ESR2FOLH1KDM6BCA2 | |
| SCHEMBL29429645 | 0.85 | KDM6B (0.62) | ESR1FOLH1KDM6BCA2MME | |
| SCHEMBL5063603 | 0.85 | KDM6B (0.62) | ESR1FOLH1KDM6BCA2MME | |
| SCHEMBL7372381 | 0.82 | MME (0.44) | ESR1ESR2FOLH1KDM6BCA2 | |
| SCHEMBL23314718 | 0.80 | FOLH1 (0.50) | FOLH1CA2MMEACELCK | |
| SCHEMBL2029160 | 0.79 | KDM6B (0.72) | ESR1ESR2KDM6BMMEACE | |
| SCHEMBL13604872 | 0.79 | ESR1 (0.53) | ESR1ESR2FOLH1KDM6BNR3C1 | |
| SCHEMBL11930754 | 0.78 | FOLH1 (0.74) | FOLH1 | |
| SCHEMBL15565481 | 0.78 | ACE (0.58) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175665-A1 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2015-06-25 | — | — | US | disclosed |
| US-8999940-B2 | Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal | IPSEN PHARMA S.A.S. (FR) | 2015-04-07 | — | — | US | disclosed |
| EP-2769986-A2 | Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal | IPSEN PHARMA S.A.S. (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-20110136725-A1 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | BIOMEASURE, INCORPORATED | 2011-06-09 | — | — | US | disclosed |
| EP-2318433-A2 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010016944-A2 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010016936-A1 | PHARMACEUTICAL COMPOSITIONS OF ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE | IPSEN PHARMA S.A.S. (FR) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175665-A1 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | GIPR, GPR119, GLP1R | ESR1 1736/4885ESR2 1206/4885FOLH1 1299/4885 |
| US-20110136725-A1 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | GIPR, GPR119, GLP1R | ESR1 1683/4885ESR2 1173/4885FOLH1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.