Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22693864 | 0.97 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDALOX15KDM4E | |
| SCHEMBL20175824 | 0.78 | CYP1A2 (0.50) | ALDH1A1CYP1A2CYP2C19LMNAMGLL | |
| SCHEMBL18288348 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1MAPTTP53CA1CA2 | |
| SCHEMBL11785800 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDALOX15KDM4E | |
| SCHEMBL24421534 | 0.71 | USP2 (0.36) | ALOX15LMNAUSP2GAA | |
| SCHEMBL23660976 | 0.71 | — | — | |
| SCHEMBL11028175 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDALOX15KDM4E | |
| SCHEMBL27442050 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPTHPGDALOX15KDM4E | |
| SCHEMBL18121411 | 0.70 | MLYCD (0.34) | ALDH1A1MAPTHPGDALOX15KDM4E | |
| SCHEMBL17636559 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303435-B1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-25 | — | — | EP | disclosed |
| US-10738001-B2 | Hydrofluoroolefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| WO-2016196240-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | RFC3, RFC2, RFC1 | ALDH1A1 1332/4885MAPT 4229/4885HPGD 1021/4885 |
| US-10738001-B2 | Hydrofluoroolefins and methods of using same | RFC3, RFC2, RFC1 | ALDH1A1 1332/4885MAPT 4229/4885HPGD 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.