Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259641 | 0.81 | PNP (0.35) | PNPPARP1ADORA3ALDH1A1ABL1 | |
| SCHEMBL2051359 | 0.79 | PNP (0.34) | PNPPARP1ADORA3ABL1RIN1 | |
| SCHEMBL20866 | 0.79 | ATAD2 (0.41) | PNPADORA3ALDH1A1HPGDATAD2 | |
| SCHEMBL2983845 | 0.79 | PNP (0.34) | PNPPARP1ADORA3ABL1RIN1 | |
| SCHEMBL1843775 | 0.79 | PNP (0.34) | PNPPARP1ADORA3ABL1RIN1 | |
| SCHEMBL20576 | 0.79 | PNP (0.34) | PNPPARP1ADORA3ABL1RIN1 | |
| SCHEMBL1301996 | 0.77 | PNP (0.33) | PNPPARP1 | |
| SCHEMBL10597939 | 0.77 | PNP (0.33) | PNPPARP1ADORA3ATAD2LMNA | |
| SCHEMBL2417369 | 0.76 | IP6K1 (0.32) | PNPPARP1ADORA3IP6K1ADORA2A | |
| SCHEMBL3291321 | 0.76 | KDM4E (0.33) | PNPPARP1ADORA3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319856-A1 | Methods and compositions for treating hepatitis c virus | Idenix (Cayman) Limited (KY) | 2011-05-11 | — | — | EP | disclosed |