SCHEMBL1843775

SCHEMBL1843775

Nc1nc2[nH]cnc2c(=O)n1S

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNP P00491 3/20 0.34
PARP1 P09874 1/20 0.33
ABL1 P00519 1/20 0.31
RIN1 Q13671 1/20 0.31
ATAD2 Q6PL18 1/20 0.31
IP6K1 Q92551 1/20 0.31
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30
ADORA2A P29274 2/20 0.30
ADORA2B P29275 2/20 0.30
PIK3CD O00329 1/20 0.30
ALPL P05186 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
TMIGD3 P0DMS9 1/20 0.30
PDE4A P27815 1/20 0.30
ADORA1 P30542 1/20 0.30
CYP2C19 P33261 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL22689091 0.86 KDM4A (0.30)
SCHEMBL8886026 0.81 PNP (0.35) PNPPARP1ABL1RIN1ATAD2
SCHEMBL1828928 0.79 PNP (0.34) PNPPARP1ABL1RIN1ATAD2
SCHEMBL20866 0.79 ATAD2 (0.41) PNPATAD2LMNACYP1A2MAPT
SCHEMBL20576 0.79 PNP (0.34) PNPPARP1ABL1RIN1ATAD2
SCHEMBL2051359 0.79 PNP (0.34) PNPPARP1ABL1RIN1ATAD2
SCHEMBL6168437 0.79 PNP (0.34) PNPPARP1ABL1RIN1ATAD2
SCHEMBL9960806 0.78 PNP (0.38) PNPPARP1ABL1RIN1LMNA
SCHEMBL7812591 0.77 ABL1 (0.33) PNPPARP1ABL1RIN1
SCHEMBL10597939 0.77 PNP (0.33) PNPPARP1ATAD2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119016735-A Gold nanocluster aggregate with multiple stimulus responsivity and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-11-26 CN claimed
WO-2022160323-A1 APPLICATION OF NUCLEOSIDE ANALOGUE IN PREPARATION OF DRUGS FOR PREVENTING OR TREATING GASTROINTESTINAL DISEASES 兰州大学 2022-08-04 WO claimed
US-20220098262-A1 ANTIBODY-TUMOR NECROSIS FACTOR alpha FUSION PROTEIN AND ITS PREPARATION AND APPLICATIONS DING, Bang (CN) 2022-03-31 US claimed
WO-2020233723-A1 QUINOLINE DERIVATIVES FOR TREATMENT OF HEAD AND NECK CANCER 正大天晴药业集团股份有限公司 (CN) 2020-11-26 WO claimed
WO-2020118605-A1 ANTIBODY-TUMOR NECROSIS FACTOR-α FUSION PROTEIN, PREPARATION METHOD THEREFOR AND USES THEREOF 丁邦 2020-06-18 WO claimed
US-6638494-B1 Iron hydroxide, ferric hydrate, iron oxide, iron mixed oxide or iron; di- or polycarboxylic acid stabilizer; aggregation prevention; antitumor and contrast agents; immune boosters, magnetic resonance imaging, cell fusion, gene transfer PILGRIMM HERBERT (DE) 2003-10-28 US claimed
EP-0888545-B1 SUPER-PARAMAGNETIC PARTICLES WITH INCREASED R 1 RELAXIVITY, PROCESSES FOR PRODUCING SAID PARTICLES AND USE THEREOF PILGRIMM HERBERT (DE) 2002-01-23 EP claimed
US-6242428-B1 NUCLEOSIDES AND NUCLEOSIDE DIMERS CONTAINING AN L-SUGAR IN AT LEAST ONE OF THE NUCLEOSIDES UNISEARCH LIMITED (AU) 2001-06-05 US claimed
EP-1069903-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE Lipitek International, Inc. (US) 2001-01-24 EP claimed
WO-1999045935-A1 NOVEL NUCLEOSIDE ANALOGS AND USES IN TREATING DISEASE LIPITEK INTERNATIONAL, INC. (US) 1999-09-16 WO claimed
EP-0689430-B1 SUPERPARAMAGNETIC PARTICLES, PROCESS FOR PRODUCING THE SAME AND THEIR USE SILICA GEL GMBH (DE) 1997-08-13 EP claimed
US-12344646-B2 Antibody-TNF α fusion protein and its preparation and applications DING, Bang (CN) 2025-07-01 US disclosed
CN-110787285-B XBP1, CD138 and CS1 peptides, pharmaceutical compositions comprising the peptides, and methods of using the peptides and compositions 达纳-法伯癌症研究所股份有限公司 2025-06-13 CN disclosed
CN-119948030-A Protease/enzyme cleavable linker-payload and protein conjugates 苏特罗生物制药公司 2025-05-06 CN disclosed
CN-119855614-A Beta-glucuronide linker-payload, protein conjugates thereof and methods thereof 苏特罗生物制药公司 2025-04-18 CN disclosed
US-20090065372-A1 METHOD FOR THE ELECTROCHEMICAL DETECTION OF TARGET NUCLEIC ACID SEQUENCES UNIVERSITÉ PARIS CITÉ (FR) 2009-03-12 US disclosed
EP-1996725-A1 METHOD FOR THE ELECTROCHEMICAL DETECTION OF TARGET NUCLEIC ACID SEQUENCES Université Paris Diderot - Paris 7 (FR) 2008-12-03 EP disclosed
WO-2007099236-A1 METHOD FOR THE ELECTROCHEMICAL DETECTION OF TARGET NUCLEIC ACID SEQUENCES UNIVERSITE PARIS DIDEROT - PARIS 7 (FR) 2007-09-07 WO disclosed
US-6638494-B1 Iron hydroxide, ferric hydrate, iron oxide, iron mixed oxide or iron; di- or polycarboxylic acid stabilizer; aggregation prevention; antitumor and contrast agents; immune boosters, magnetic resonance imaging, cell fusion, gene transfer PILGRIMM HERBERT (DE) 2003-10-28 US disclosed
US-5391723-A Oligonucleotide conjugates NEORX CORPORATION (US) 1995-02-21 US disclosed