Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL9644546 | 0.81 | — | — | |
| SCHEMBL20866 | 0.80 | ATAD2 (0.41) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL2385669 | 0.78 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL8886026 | 0.78 | PNP (0.35) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL3259641 | 0.78 | PNP (0.35) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL6168437 | 0.77 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL20576 | 0.77 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL2051359 | 0.77 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL2983845 | 0.77 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT | |
| SCHEMBL1843775 | 0.77 | PNP (0.34) | PNPATAD2LMNACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145739-B1 | NOVEL ANTIVIRAL AGENTS | SRI INTERNATIONAL (US) | 1989-02-08 | — | — | EP | disclosed |
| EP-0274025-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-13 | — | — | EP | disclosed |
| EP-0273169-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0272446-A1 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-06-29 | — | — | EP | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |