Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 11/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15810832 | 1.00 | P2RY6 (0.42) | P2RY6DNPH1P2RY14EIF4ENT5E | |
| SCHEMBL18158964 | 1.00 | P2RY6 (0.42) | P2RY6DNPH1P2RY14EIF4ENT5E | |
| SCHEMBL14929352 | 0.90 | DNPH1 (0.43) | P2RY6DNPH1P2RY14EIF4ENT5E | |
| SCHEMBL14946382 | 0.90 | DNPH1 (0.43) | P2RY6DNPH1P2RY14EIF4ENT5E | |
| SCHEMBL18574182 | 0.90 | DNPH1 (0.43) | P2RY6DNPH1P2RY14EIF4ENT5E | |
| SCHEMBL18289441 | 0.88 | P2RY6 (0.41) | P2RY6DNPH1P2RY14EIF4E | |
| SCHEMBL18289614 | 0.88 | P2RY6 (0.41) | P2RY6DNPH1P2RY14EIF4E | |
| SCHEMBL15836223 | 0.87 | DNPH1 (0.53) | P2RY6DNPH1EIF4E | |
| SCHEMBL14929195 | 0.87 | DNPH1 (0.53) | P2RY6DNPH1EIF4E | |
| SCHEMBL10133476 | 0.87 | DNPH1 (0.53) | P2RY6DNPH1EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255194-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNATX INC (US) | 2019-08-22 | — | — | US | disclosed |
| EP-2931319-B1 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNATX INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20170175129-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS INC (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255194-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, RNGTT, NSUN3 | P2RY6 2112/4885DNPH1 2277/4885P2RY14 2371/4885 |
| US-20170175129-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | NSUN2, RNGTT, NSUN3 | P2RY6 2112/4885DNPH1 2277/4885P2RY14 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.