Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10309833 | 0.96 | PRSS1 (0.36) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL17014130 | 0.94 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10309866 | 0.93 | PRSS1 (0.36) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10309850 | 0.93 | F2 (0.36) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10309861 | 0.91 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10309843 | 0.91 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL25967790 | 0.90 | PRSS1 (0.36) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10309818 | 0.90 | PRSS1 (0.36) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL9971307 | 0.83 | KEAP1 (0.40) | HSP90AB1KEAP1GIGYF2SENP1SMN1; SMN2 | |
| SCHEMBL30929050 | 0.82 | HSP90AB1 (0.43) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285574-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2023-09-14 | — | — | US | disclosed |
| US-11723981-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-08-15 | — | — | US | disclosed |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285574-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | CD44, EPCAM, ALG1 | PRSS1 3076/4885PRSS2 3014/4885PRSS3 2218/4885 |
| US-11723981-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | TNF, TNFRSF1A, TNFSF11 | PRSS1 2716/4885PRSS2 2651/4885PRSS3 2134/4885 |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | TNF, TNFRSF1A, TNFSF11 | PRSS1 2716/4885PRSS2 2651/4885PRSS3 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.