Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.36 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16141184 | 0.89 | HLCS (0.39) | KEAP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30929049 | 0.88 | HSP90AB1 (0.43) | KEAP1HSP90AB1 | |
| SCHEMBL30929050 | 0.88 | HSP90AB1 (0.43) | KEAP1HSP90AB1 | |
| SCHEMBL30205084 | 0.88 | KEAP1 (0.40) | KEAP1SENP1TDP1HSP90AB1ALDH1A1 | |
| SCHEMBL15445418 | 0.84 | KEAP1 (0.37) | KEAP1SENP1TDP1HSP90AB1ITGB1 | |
| SCHEMBL23812201 | 0.83 | TDP1 (0.47) | KEAP1TDP1ALDH1A1 | |
| SCHEMBL16478559 | 0.83 | TDP1 (0.47) | KEAP1TDP1ALDH1A1 | |
| SCHEMBL21606765 | 0.83 | TDP1 (0.42) | KEAP1TDP1ALDH1A1 | |
| SCHEMBL30205123 | 0.83 | TDP1 (0.42) | KEAP1TDP1ALDH1A1 | |
| SCHEMBL30331593 | 0.83 | TDP1 (0.42) | KEAP1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773219-B2 | Functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-03 | — | — | US | disclosed |
| US-20230285574-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2023-09-14 | — | — | US | disclosed |
| US-11723981-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-08-15 | — | — | US | disclosed |
| US-9849187-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2017-12-26 | — | — | US | disclosed |
| US-9790324-B2 | Functionalized polymers | QUIAPEG AB | 2017-10-17 | — | — | US | disclosed |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2016-12-08 | — | — | US | disclosed |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | FISH & RICHARDSON PC | 2016-12-08 | — | — | US | disclosed |
| US-9220789-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-9220789-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | QUIAPEG PHARMACEUTICALS AB (SE) | 2015-12-29 | — | — | US | disclosed |
| US-20150232615-A1 | Functionalized Polymers | QUIAPEG AB (SE) | 2015-08-20 | — | — | US | disclosed |
| US-20150232615-A1 | Functionalized Polymers | QUIAPEG AB (SE) | 2015-08-20 | — | — | US | disclosed |
| US-20150147345-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2015-05-28 | — | — | US | disclosed |
| US-20150147345-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2015-05-28 | — | — | US | disclosed |
| US-20140030278-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2014-01-30 | — | — | US | disclosed |
| US-20140030278-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | QUIAPEG AB (SE) | 2014-01-30 | — | — | US | disclosed |
| WO-2012080836-A2 | FUNCTIONALIZED POLYMERS | KWIATKOWSKI MAREK (SE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285574-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | CD44, EPCAM, ALG1 | KEAP1 4080/4885SENP1 1472/4885TDP1 1794/4885 |
| US-20150147345-A1 | CONJUGATES OF BIOLOGICALLY ACTIVE MOLECULES TO FUNCTIONALIZED POLYMERS | CD44, EPCAM, ALG1 | KEAP1 4080/4885SENP1 1472/4885TDP1 1794/4885 |
| US-11723981-B2 | Conjugates of tumor necrosis factor inhibitors to functionalized polymers | TNF, TNFRSF1A, TNFSF11 | KEAP1 3499/4885SENP1 598/4885TDP1 2625/4885 |
| US-11773219-B2 | Functionalized polymers | PARG, PUF60, PCBP1 | KEAP1 4387/4885SENP1 2525/4885TDP1 1616/4885 |
| US-20160354477-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | TNF, TNFRSF1A, TNFSF11 | KEAP1 3499/4885SENP1 598/4885TDP1 2625/4885 |
| US-20140030278-A1 | CONJUGATES OF TUMOR NECROSIS FACTOR INHIBITORS TO FUNCTIONALIZED POLYMERS | TNF, TNFRSF1A, TNFSF11 | KEAP1 3499/4885SENP1 598/4885TDP1 2625/4885 |
| US-20150232615-A1 | Functionalized Polymers | PARG, PUF60, PCBP1 | KEAP1 4387/4885SENP1 2525/4885TDP1 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.