Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.39 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929049 | 1.00 | HSP90AB1 (0.43) | HSP90AB1PKMKEAP1PRSS1PRSS2 | |
| SCHEMBL9971307 | 0.88 | KEAP1 (0.40) | HSP90AB1KEAP1 | |
| SCHEMBL23812201 | 0.84 | TDP1 (0.47) | PKMKEAP1 | |
| SCHEMBL16478559 | 0.84 | TDP1 (0.47) | PKMKEAP1 | |
| SCHEMBL30205123 | 0.84 | TDP1 (0.42) | PKMKEAP1 | |
| SCHEMBL30331593 | 0.84 | TDP1 (0.42) | PKMKEAP1 | |
| SCHEMBL21606765 | 0.84 | TDP1 (0.42) | PKMKEAP1 | |
| SCHEMBL30205084 | 0.83 | KEAP1 (0.40) | HSP90AB1KEAP1TPSAB1FOLH1 | |
| SCHEMBL16141184 | 0.83 | HLCS (0.39) | KEAP1 | |
| SCHEMBL18289486 | 0.82 | PRSS1 (0.38) | HSP90AB1PKMKEAP1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11965886-B2 | Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2024-04-23 | — | — | US | disclosed |