Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874720 | 0.84 | POLB (0.48) | POLBNLRP3CYP4F2CYP4A11BACE1 | |
| SCHEMBL25941557 | 0.83 | POLB (0.42) | POLBNLRP3CYP4F2CYP4A11BACE1 | |
| SCHEMBL18290075 | 0.78 | POLB (0.48) | POLBNLRP3BACE1HTTMAPT | |
| SCHEMBL24106111 | 0.77 | MAPT (0.38) | POLBNLRP3CYP4F2CYP4A11BACE1 | |
| SCHEMBL25571434 | 0.77 | POLB (0.40) | POLBNLRP3BACE1HTTKDM4E | |
| SCHEMBL4317657 | 0.75 | POLB (0.56) | POLBNLRP3BACE1KDM4EGAA | |
| SCHEMBL14369565 | 0.75 | CA2 (0.45) | POLBNLRP3CYP4F2CYP4A11BACE1 | |
| SCHEMBL25571438 | 0.75 | POLB (0.41) | POLBNLRP3CYP4F2CYP4A11BACE1 | |
| SCHEMBL10875516 | 0.74 | POLB (0.58) | POLBNLRP3BACE1HTTMAPT | |
| SCHEMBL27698991 | 0.74 | KDM4E (0.41) | POLBNLRP3BACE1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193136-A1 | HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS | ANTIBIOTX APS (DK) | 2016-12-08 | — | — | WO | disclosed |