Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26800387 | 0.82 | POLB (0.38) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL29289982 | 0.81 | HTT (0.42) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL27698991 | 0.80 | KDM4E (0.41) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL4317657 | 0.78 | POLB (0.56) | POLBNLRP3KDM4EHSD17B10GAA | |
| SCHEMBL18290079 | 0.78 | POLB (0.46) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL14136180 | 0.78 | LMNA (0.43) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL27255623 | 0.78 | ELANE (0.39) | POLBNLRP3TTR | |
| SCHEMBL24812562 | 0.78 | KDM4E (0.40) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL2351331 | 0.78 | POLB (0.48) | POLBNLRP3HTTKDM4EHSD17B10 | |
| SCHEMBL10875516 | 0.77 | POLB (0.58) | POLBNLRP3HTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157997-A1 | NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE | ANTIBIOTX APS (DK) | 2017-09-21 | — | — | WO | disclosed |
| WO-2016193136-A1 | HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS | ANTIBIOTX APS (DK) | 2016-12-08 | — | — | WO | disclosed |