Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290223 | 0.75 | SOD1 (0.34) | FDPSSOD1KARS1 | |
| SCHEMBL16006769 | 0.74 | KARS1 (0.43) | FDPSSOD1KARS1 | |
| SCHEMBL18290220 | 0.72 | SOD1 (0.33) | SOD1KARS1 | |
| SCHEMBL18290199 | 0.67 | KARS1 (0.40) | FDPSSOD1KARS1 | |
| SCHEMBL18290358 | 0.64 | — | — | |
| SCHEMBL18290211 | 0.63 | SOD1 (0.53) | FDPSSOD1KARS1 | |
| SCHEMBL18290371 | 0.62 | — | — | |
| SCHEMBL18290245 | 0.61 | LPAR1 (0.32) | — | |
| SCHEMBL18290286 | 0.60 | — | — | |
| SCHEMBL18290235 | 0.59 | SOD1 (0.38) | SOD1KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |