Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707610 | 0.87 | CYP3A4 (0.41) | SOD1TP53CYP3A4 | |
| Dehydroabietinol Acetate SCHEMBL14648811 | 0.59 | KARS1 (0.72) | TP53CYP3A4 | |
| SCHEMBL14652333 | 0.59 | NR1H2 (0.49) | TP53CYP3A4NR1H2NR1H3 | |
| SCHEMBL18290302 | 0.56 | SOD1 (0.47) | SOD1 | |
| SCHEMBL17112802 | 0.55 | CYP4F2 (0.62) | — | |
| SCHEMBL18290292 | 0.55 | SOD1 (1.00) | SOD1CYP3A4 | |
| SCHEMBL15389602 | 0.55 | KARS1 (0.55) | SOD1TP53CYP3A4 | |
| SCHEMBL15389776 | 0.55 | KARS1 (0.55) | SOD1TP53CYP3A4 | |
| SCHEMBL14112006 | 0.55 | PTGS1 (0.43) | PAX8TLR9F10NR1H2NR1H3 | |
| SCHEMBL19770995 | 0.55 | CYP3A4 (0.72) | CYP3A4NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |