Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.47 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290294 | 0.76 | SOD1 (0.43) | SOD1KARS1FDPS | |
| SCHEMBL16006731 | 0.68 | CYP19A1 (0.60) | SOD1KARS1FDPSCYP19A1PTGES | |
| SCHEMBL18290200 | 0.67 | SOD1 (0.76) | SOD1KARS1FDPSCYP19A1PTGES | |
| SCHEMBL18290243 | 0.65 | SOD1 (0.45) | SOD1KARS1FDPSCYP19A1PTGES | |
| SCHEMBL18290292 | 0.64 | SOD1 (1.00) | SOD1KARS1FDPS | |
| SCHEMBL18290208 | 0.64 | SOD1 (1.00) | SOD1KARS1FDPS | |
| SCHEMBL18290209 | 0.64 | KARS1 (0.50) | SOD1KARS1FDPSCYP19A1PTGES | |
| SCHEMBL18290199 | 0.61 | KARS1 (0.40) | SOD1KARS1FDPSCYP19A1MEN1 | |
| Sugiol SCHEMBL17407685 | 0.60 | SOD1 (0.58) | SOD1KARS1FDPSCYP19A1PTGES | |
| Sugiol SCHEMBL28605319 | 0.60 | SOD1 (0.58) | SOD1KARS1FDPSCYP19A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |