Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287259 | 0.83 | GAA (0.40) | MAPTKDM4EALDH1A1TDP1PTK2 | |
| SCHEMBL18287261 | 0.80 | WEE1 (0.32) | PTK2MEN1KMT2A | |
| SCHEMBL12435103 | 0.79 | MAPT (0.51) | ALOX15MAPTKDM4EALDH1A1GLA | |
| SCHEMBL25089824 | 0.74 | IRAK4 (0.43) | KDM4EALDH1A1HSD17B10POLBL3MBTL1 | |
| SCHEMBL17291900 | 0.73 | KDM4E (0.44) | ALOX15MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12109355 | 0.73 | MAPT (0.60) | ALOX15MAPTKDM4EALDH1A1GLA | |
| SCHEMBL17291903 | 0.73 | SMN1; SMN2 (0.39) | ALOX15MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL25089929 | 0.73 | SMN1; SMN2 (0.44) | MAPTKDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL16892742 | 0.72 | MAPT (0.56) | ALOX15MAPTKDM4EALDH1A1GLA | |
| SCHEMBL19717457 | 0.71 | MYC (0.54) | ALOX15MAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9711739-B2 | Tetradentate metal complexes containing indoloacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | PDCD2L, AP3M1, AP3D1 | ALOX15 4822/4885MAPT 124/4885KDM4E 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.