Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287259 | 0.84 | GAA (0.40) | PTK2MEN1KMT2A | |
| SCHEMBL18290497 | 0.80 | ALOX15 (0.44) | PTK2MEN1KMT2A | |
| SCHEMBL12435097 | 0.78 | PGR (0.40) | P2RY1MEN1KMT2A | |
| SCHEMBL17291903 | 0.74 | SMN1; SMN2 (0.39) | MEN1KMT2A | |
| SCHEMBL25089929 | 0.74 | SMN1; SMN2 (0.44) | MEN1KMT2A | |
| SCHEMBL18287257 | 0.72 | SMN1; SMN2 (0.39) | MEN1KMT2A | |
| SCHEMBL31611978 | 0.72 | SMN1; SMN2 (0.39) | MEN1KMT2A | |
| SCHEMBL12109361 | 0.72 | PDK2 (0.39) | P2RY1BUB1 | |
| SCHEMBL16892754 | 0.71 | PDK2 (0.42) | BUB1 | |
| SCHEMBL30631793 | 0.71 | PDK2 (0.42) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006246-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-01-04 | — | — | US | disclosed |
| US-9711739-B2 | Tetradentate metal complexes containing indoloacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9711739-B2 | Tetradentate metal complexes containing indoloacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | PDCD2L, AP3M1, AP3D1 | WEE1 1792/4885PLK1 516/4885P2RY1 1095/4885 |
| US-20180006246-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | PDCD2L, AP3M1, AP3D1 | WEE1 1792/4885PLK1 516/4885P2RY1 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.