SCHEMBL16892742

SCHEMBL16892742

COC(=O)c1ccccc1Nc1ccc2c(c1)C(C)(C)c1ccccc1-2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.56
▸ ALOX15 P16050 1/20 0.56
▸ SIRT2 Q8IXJ6 1/20 0.46
▸ KDM4E B2RXH2 5/20 0.46
▸ POLB P06746 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ KMT2A Q03164 1/20 0.43
▸ HPGD P15428 1/20 0.42
▸ MAPK10 P53779 1/20 0.42
▸ GLA P06280 1/20 0.41
▸ PDK2 Q15119 3/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ AURKA O14965 1/20 0.41
▸ HSD17B10 Q99714 3/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ PTK2 Q05397 1/20 0.40
▸ GAA P10253 4/20 0.40
▸ CTSV O60911 1/20 0.40
▸ CTSL P07711 1/20 0.40
▸ TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12109355 0.96 MAPT (0.60) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL12109299 0.94 MAPT (0.57) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL13828515 0.90 MAPT (0.53) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL12109325 0.88 MAPT (0.51) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL20181951 0.82 PDK2 (0.44) MAPTPDK2GAASLC6A2SLC6A4
SCHEMBL15119781 0.82 PDK2 (0.39) MAPTALOX15SIRT2KMT2APDK2
SCHEMBL12435103 0.78 MAPT (0.51) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL21324338 0.78 MAPT (0.60) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL13224505 0.78 MAPT (0.89) MAPTALOX15SIRT2KDM4EPOLB
SCHEMBL29462256 0.78 PDK2 (0.51) MAPTALOX15KMT2AHPGDPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185324-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-10-04 — — EP disclosed
CN-110467590-B Heteroaromatic compound and organic electroluminescent module using the same 机光科技股份有限公司 2021-08-13 — — CN disclosed
US-11005047-B2 Heteroaromatic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-05-11 — — US disclosed
US-11005047-B2 Heteroaromatic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-05-11 — — US disclosed
US-10844043-B2 Heteroaromatic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2020-11-24 — — US disclosed
US-10844043-B2 Heteroaromatic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2020-11-24 — — US disclosed
CN-110467590-A Heteroaromatics and the organic EL component for using it LUMINESCENCE TECH CORP 2019-11-19 — — CN disclosed
US-20190348609-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-11-14 — — US disclosed
US-20190348609-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-11-14 — — US disclosed
CN-110396061-A Heteroaromatics and the organic EL component for using the compound LUMINESCENCE TECH CORP 2019-11-01 — — CN disclosed
US-20190322641-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-10-24 — — US disclosed
US-10424742-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-24 — — US disclosed
CN-110218185-A Heteroaromatics and the organic EL component for using it 机光科技股份有限公司 2019-09-10 — — CN disclosed
US-20190273210-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-09-05 — — US disclosed
US-20190273210-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-09-05 — — US disclosed
EP-2894155-B1 COMPOUND HAVING INDENO ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2018-11-14 — — EP disclosed
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-21 — — US disclosed
EP-3185324-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-28 — — EP disclosed
US-20150249218-A1 COMPOUND HAVING INDENOACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-03 — — US disclosed
EP-2894155-A1 COMPOUND HAVING INDENO ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2015-07-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844043-B2 Heteroaromatic compound and organic electroluminescence device using the same VDAC1, TRPC6, TRPC5 MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC43A1, KCNN4 MAPT 3749/4885ALOX15 524/4885SIRT2 3866/4885
US-11005047-B2 Heteroaromatic compound and organic electroluminescence device using the same ARNT, TRPC6, DDT MAPT 1888/4885ALOX15 756/4885SIRT2 2806/4885
US-20190322641-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME VDAC1, TRPC6, TRPC5 MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885
US-20190348609-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ARNT, TRPC6, DDT MAPT 1888/4885ALOX15 756/4885SIRT2 2806/4885
US-20190273210-A1 HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME VDAC1, TRPC6, TRPC5 MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885
US-20150249218-A1 COMPOUND HAVING INDENOACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE KCNH2, KCNH3, INHA MAPT 1736/4885ALOX15 762/4885SIRT2 4470/4885
US-10424742-B2 Organic electroluminescent device AHR, SLC43A1, KCNN4 MAPT 3749/4885ALOX15 524/4885SIRT2 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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