Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287261 | 0.84 | WEE1 (0.32) | KMT2APTK2MEN1 | |
| SCHEMBL18290497 | 0.83 | ALOX15 (0.44) | TDP1MAPTKMT2APTK2MAPK10 | |
| SCHEMBL25089929 | 0.81 | SMN1; SMN2 (0.44) | GAASMN1; SMN2TDP1HTTMAPT | |
| SCHEMBL17291903 | 0.76 | SMN1; SMN2 (0.39) | GAASMN1; SMN2TP53TDP1MAPT | |
| SCHEMBL18287257 | 0.76 | SMN1; SMN2 (0.39) | GAASMN1; SMN2TP53HTTMAPT | |
| SCHEMBL31611978 | 0.76 | SMN1; SMN2 (0.39) | GAASMN1; SMN2TP53HTTMAPT | |
| SCHEMBL17291900 | 0.74 | KDM4E (0.44) | SMN1; SMN2TP53HTTMAPTKMT2A | |
| SCHEMBL17525283 | 0.74 | TP53 (0.44) | GAASMN1; SMN2TP53MAPTMAPK10 | |
| SCHEMBL28617183 | 0.72 | SMN1; SMN2 (0.37) | GAASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL24894123 | 0.70 | IRAK4 (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006246-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-01-04 | — | — | US | disclosed |
| US-9711739-B2 | Tetradentate metal complexes containing indoloacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160359120-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | PDCD2L, AP3M1, AP3D1 | GAA 4517/4885SMN1; SMN2 3478/4885TP53 475/4885 |
| US-20180006246-A1 | TETRADENTATE METAL COMPLEXES CONTAINING INDOLOACRIDINE AND ITS ANALOGUES | PDCD2L, AP3M1, AP3D1 | GAA 4517/4885SMN1; SMN2 3478/4885TP53 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.