SCHEMBL182920

SCHEMBL182920

O=C(O)CCCCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.55
HDAC4 P56524 3/20 0.55
HDAC1 Q13547 3/20 0.55
HDAC7 Q8WUI4 3/20 0.55
HDAC2 Q92769 3/20 0.55
HDAC10 Q969S8 3/20 0.55
HDAC11 Q96DB2 3/20 0.55
HDAC8 Q9BY41 3/20 0.55
HDAC6 Q9UBN7 3/20 0.55
HDAC9 Q9UKV0 3/20 0.55
HDAC5 Q9UQL6 3/20 0.55
TUBB4A P04350 2/20 0.55
TUBB P07437 2/20 0.55
TUBA3C P0DPH7 2/20 0.55
TUBA1B P68363 2/20 0.55
TUBA4A P68366 2/20 0.55
TUBB4B P68371 2/20 0.55
TUBB3 Q13509 2/20 0.55
TUBB2A Q13885 2/20 0.55
TUBB8 Q3ZCM7 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31461255 0.95 MAPT (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL23668266 0.95 MAPT (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL179725 0.88 MAPT (0.60) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL31461256 0.88 MAPT (0.60) HDAC3HDAC4HDAC1HDAC7HDAC2
Phosphonic Acid SCHEMBL5566523 0.83 MAPT (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8345041 0.83 MAPT (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL27452810 0.81 MAPT (0.54) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5087842 0.78 MEN1 (0.55) MAPTMEN1KMT2AP2RX4P2RX1
SCHEMBL284853 0.77 HDAC3 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4090113 0.77 P2RX4 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US claimed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US claimed
US-RE49466-E1 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2023-03-21 US disclosed
WO-2020028619-A1 SPARC BASED MICROORGANISM DETECTION METHOD BECKMAN COULTER, INC. (US) 2020-02-06 WO disclosed
US-10036708-B2 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2018-07-31 US disclosed
EP-2027453-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
EP-2021778-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
EP-2401392-B1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER INC (US) 2017-01-25 EP disclosed
US-20150212005-A1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER, INC. 2015-07-30 US disclosed
US-9029092-B2 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2015-05-12 US disclosed
US-8377647-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2013-02-19 US disclosed
US-6872828-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2005-03-29 US disclosed
US-6858733-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2005-02-22 US disclosed
EP-1456176-A4 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN INC (US) 2004-11-03 EP disclosed
EP-1456176-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2004-09-15 EP disclosed
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2004-09-09 US disclosed
CN-1492857-A Improved compounds for generating chemiluminescence with peroxidase 鲁米根公司 2004-04-28 CN disclosed
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2003-09-11 US disclosed
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase AKHAVAN-TAFTI HASHEM (US) 2003-09-11 US disclosed
WO-2003053934-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885HDAC4 4295/4885HDAC1 3692/4885
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885HDAC4 4295/4885HDAC1 3692/4885
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 HDAC3 4141/4885HDAC4 4295/4885HDAC1 3692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.