Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338300 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RECQLRAB9APRMT5 | |
| SCHEMBL29407958 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RECQLRAB9APRMT5 | |
| SCHEMBL28131480 | 0.75 | ALDH1A1 (0.43) | MAPTNPC1RECQLRAB9APRMT5 | |
| SCHEMBL23618591 | 0.74 | NPC1 (0.46) | MAPTLMNANPC1RECQLRAB9A | |
| SCHEMBL17532740 | 0.74 | MAPT (0.49) | MAPTLMNANPC1RECQLRAB9A | |
| SCHEMBL28088960 | 0.74 | MAPT (0.46) | MAPTLMNANPC1RECQLRAB9A | |
| SCHEMBL4677179 | 0.72 | PDE10A (0.69) | MAPTLMNANPC1RAB9ALOXL2 | |
| SCHEMBL5470832 | 0.71 | PRMT5 (0.56) | MAPTLMNANPC1RECQLRAB9A | |
| SCHEMBL31379757 | 0.71 | SMN1; SMN2 (0.56) | MAPTLMNANPC1RECQLRAB9A | |
| SCHEMBL24596450 | 0.71 | SMN1; SMN2 (0.56) | MAPTLMNANPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303353-B1 | PROCESS | JOHNSON MATTHEY PLC (GB) | 2022-01-12 | — | — | EP | disclosed |
| US-10428098-B2 | Processes for preparing and using ruthenium and osmium complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-10-01 | — | — | US | disclosed |
| WO-2019043414-A1 | PROCESS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-03-07 | — | — | WO | disclosed |
| US-20180148465-A1 | PROCESS | UNIVERSITA DEGLI STUDI DI UDINE (IT) | 2018-05-31 | — | — | US | disclosed |
| US-20180148465-A1 | PROCESS | UNIVERSITA DEGLI STUDI DI UDINE (IT) | 2018-05-31 | — | — | US | disclosed |
| WO-2016193762-A1 | PROCESS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428098-B2 | Processes for preparing and using ruthenium and osmium complexes | OSTC, OTC, ORC3 | MAPT 3267/4885LMNA 4381/4885NPC1 1821/4885 |
| US-20180148465-A1 | PROCESS | OSTC, AP2S1, LGALS4 | MAPT 2770/4885LMNA 4467/4885NPC1 1831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.