Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20997478 | 0.81 | ALOX12 (0.54) | PARLALOX12ALDH1A1TSHRPKM | |
| SCHEMBL1929687 | 0.81 | ALOX12 (0.54) | PARLALOX12ALDH1A1TSHRPKM | |
| Hydrochloric Acid SCHEMBL6606867 | 0.79 | ALOX12 (0.53) | PARLALOX12ALDH1A1TSHRPKM | |
| SCHEMBL9386766 | 0.75 | ALOX12 (0.49) | PARLALOX12ALDH1A1TSHRPKM | |
| SCHEMBL6343082 | 0.73 | ALDH1A1 (0.43) | ALDH1A1PKMGAAMAPK1HPGD | |
| SCHEMBL142445 | 0.73 | ALDH1A1 (0.47) | ALDH1A1PKMMAPK1KMT2ADDB1 | |
| SCHEMBL11323517 | 0.73 | ALDH1A1 (0.47) | ALDH1A1PKMMAPK1KMT2ADDB1 | |
| SCHEMBL1279658 | 0.71 | ALDH1A1 (0.46) | ALDH1A1PKMMAPK1KMT2ADDB1 | |
| SCHEMBL19763139 | 0.71 | ALDH1A1 (0.50) | ALDH1A1PKMMAPK1KMT2ADDB1 | |
| SCHEMBL30293247 | 0.71 | POLB (0.56) | ALOX12ALDH1A1TSHRPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016197078-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | WO | disclosed |