Furilazole

Furilazole

SCHEMBL1829319

CC1(C)OC(c2ccco2)CN1C(=O)C(Cl)Cl.FC(F)(F)/C(=N\OCC1OCCO1)c1ccc(Cl)cc1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furilazole SCHEMBL12490154 0.77 ALDH1A1 (0.38) ADORA2B
Furilazole SCHEMBL124162 0.77 ALDH1A1 (0.38) ADORA2B
Furilazole SCHEMBL167569 0.77 ALDH1A1 (0.38) ADORA2B
Furilazole SCHEMBL8462067 0.77 ALDH1A1 (0.38) ADORA2B
SCHEMBL5933972 0.74 NPC1 (0.33)
SCHEMBL23888 0.74 NPC1 (0.33)
SCHEMBL175984 0.74 NPC1 (0.33)
SCHEMBL27260520 0.70 ADORA2B (0.37) ADORA2B
SCHEMBL12394453 0.70 ALDH1A1 (0.40) ADORA2B
SCHEMBL10736377 0.70 NPC1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320736-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYANILIDES Bayer CropScience AG (DE) 2011-05-18 EP disclosed
EP-2317855-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-05-11 EP disclosed
WO-2010017928-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017924-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017930-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed