Furilazole

Furilazole

SCHEMBL167569

CC1(C)O[C@H](c2ccco2)CN1C(=O)C(Cl)Cl

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
CYP2C19 P33261 1/20 0.38
NPC1 O15118 1/20 0.37
KDM4E B2RXH2 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PKM P14618 2/20 0.35
ADORA2B P29275 10/20 0.33
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 2/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PABPC1 P11940 1/20 0.33
EIF4H Q15056 1/20 0.33
ALOX5 P09917 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furilazole SCHEMBL8462067 1.00 ALDH1A1 (0.38) ALDH1A1CYP2C19NPC1KDM4ENPSR1
Furilazole SCHEMBL124162 1.00 ALDH1A1 (0.38) ALDH1A1CYP2C19NPC1KDM4ENPSR1
Furilazole SCHEMBL12490154 1.00 ALDH1A1 (0.38) ALDH1A1CYP2C19NPC1KDM4ENPSR1
SCHEMBL12394453 0.91 ALDH1A1 (0.40) ALDH1A1CYP2C19NPC1KDM4ENPSR1
SCHEMBL27260520 0.84 ADORA2B (0.37) ALDH1A1CYP2C19NPC1KDM4ENPSR1
SCHEMBL7946105 0.82 YAP1 (0.43) ALDH1A1CYP2C19NPC1KDM4ENPSR1
SCHEMBL856664 0.80 ALDH1A1 (0.40) ALDH1A1KDM4EKMT2AMEN1POLB
SCHEMBL11019917 0.77 MAPK1 (0.40) ALDH1A1KDM4E
Furilazole SCHEMBL14690557 0.77 HTT (0.35) ADORA2BHTT
Furilazole SCHEMBL1829319 0.77 ADORA2B (0.32) ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 987 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11937599-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2024-03-26 US claimed
US-11419331-B2 Microencapsulated acetamide herbicides MONSANTO TECHNOLOGY LLC (US) 2022-08-23 US claimed
US-20220079148-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2022-03-17 US claimed
US-11129381-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2021-09-28 US claimed
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-07-30 US claimed
US-20200163331-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-05-28 US claimed
EP-2210492-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-07-28 EP claimed
EP-2191716-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-1213966-B1 NEW HERBICIDAL COMPOSITIONS BAYER CROPSCIENCE LTD (GB) 2006-04-19 EP claimed
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2026-05-28 US disclosed
EP-3947350-B1 SUBSTITUTED 2-HETEROARYL AMINOBENZENES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS BAYER AG (DE) 2026-05-27 EP disclosed
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2026-05-21 US disclosed
US-20260137080-A1 EARLY APPLICATIONS OF ENCAPSULATED ACETAMIDES FOR REDUCED INJURY IN CROPS MONSANTO TECH LLC (US) 2026-05-21 US disclosed
US-20260114444-A1 PESTICIDAL COMPOSITIONS MONSANTO TECHNOLOGY LLC (US) 2026-04-30 US disclosed
US-20020115567-A1 Substituted 2-amino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators AVENTIS CROPSCIENCE GMBH (DE) 2002-08-22 US disclosed
US-20020016263-A1 Liquid formulations AVENTIS CROPSCIENCE GMBH (DE) 2002-02-07 US disclosed
US-20010011063-A1 Substituted 2,4-diamino-1,3,5-triazines, processes for their preparation and their use as herbicides and plant growth regulators AVENTIS CROPSCIENCE GMBH (DE) 2001-08-02 US disclosed
EP-1097117-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2001-05-09 EP disclosed
WO-2000003975-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2000-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138958-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES CBR1, CBR3, HDHD5 ALDH1A1 148/4885CYP2C19 1914/4885NPC1 2125/4885
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS FOXM1, CSDE1, RCC1 ALDH1A1 692/4885CYP2C19 284/4885NPC1 2719/4885
US-20200163331-A1 MICROENCAPSULATED HERBICIDES HACL2, ACACB, HDHD5 ALDH1A1 491/4885CYP2C19 1535/4885NPC1 3879/4885
US-11129381-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 ALDH1A1 491/4885CYP2C19 1535/4885NPC1 3879/4885
US-20260137080-A1 EARLY APPLICATIONS OF ENCAPSULATED ACETAMIDES FOR REDUCED INJURY IN CROPS SRM, PFAS, ACMSD ALDH1A1 1175/4885CYP2C19 2007/4885NPC1 3987/4885
US-20010011063-A1 Substituted 2,4-diamino-1,3,5-triazines, processes for their preparation and their use as herbicides and plant growth regulators DDT, DAZAP1, SAT1 ALDH1A1 314/4885CYP2C19 3399/4885NPC1 4813/4885
US-20260114444-A1 PESTICIDAL COMPOSITIONS NOTUM, WEE1, DDT ALDH1A1 801/4885CYP2C19 1944/4885NPC1 3344/4885
US-11937599-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 ALDH1A1 491/4885CYP2C19 1535/4885NPC1 3879/4885
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES HDHD5, HACL2, ACAA2 ALDH1A1 316/4885CYP2C19 1336/4885NPC1 4122/4885
US-20020016263-A1 Liquid formulations SLC25A1, SLC16A1, OTC ALDH1A1 1270/4885CYP2C19 2314/4885NPC1 815/4885
US-20020115567-A1 Substituted 2-amino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators QSOX1, BCL2A1, BCL2L2 ALDH1A1 399/4885CYP2C19 2775/4885NPC1 4751/4885
US-11419331-B2 Microencapsulated acetamide herbicides HDHD5, HACL2, ACAA2 ALDH1A1 316/4885CYP2C19 1336/4885NPC1 4122/4885
US-20220079148-A1 MICROENCAPSULATED HERBICIDES HACL2, ACACB, HDHD5 ALDH1A1 491/4885CYP2C19 1535/4885NPC1 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.