SCHEMBL1829599

SCHEMBL1829599

CCCCC=C[Si](Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
FAAH O00519 3/20 0.36
TRPV1 Q8NER1 2/20 0.36
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
LPAR2 Q9HBW0 2/20 0.31
LPAR3 Q9UBY5 2/20 0.31
PPARA Q07869 1/20 0.31
LPAR1 Q92633 1/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829597 1.00 TSHR (0.38) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL10883152 0.92 FAAH (0.44) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL269212 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL3478032 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL3179741 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL4621843 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL1615752 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL660903 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL2750368 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3
SCHEMBL3478033 0.90 FAAH (0.48) TSHRFAAHTRPV1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262515-B A kind of granular random/stereoblock polystyrene preparation method 沈阳化工大学 2017-08-08 CN claimed
EP-0258418-A4 ELASTOMER-PLASTIC BLENDS. EXXON RESEARCH ENGINEERING CO (US) 1989-06-26 EP claimed
EP-0258418-A1 ELASTOMER-PLASTIC BLENDS ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1988-03-09 EP claimed
EP-0240638-A2 Olefinic chlorosilane and olefinic halide functional group containing polymers and method of forming the same EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-10-14 EP claimed
WO-1987005312-A1 ELASTOMER-PLASTIC BLENDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-09-11 WO claimed
CN-111825710-B Alkoxysilyl group-containing organosilane compound, method for producing same, composition containing same, and cured product 信越化学工业株式会社 2024-08-23 CN disclosed
US-11739184-B2 Polysiloxazane compound having alkoxysilyl group, process for producing same, and composition and cured product including same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-29 US disclosed
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed
CN-114797807-A Liquid chromatography stationary phase, preparation method and application thereof 华谱科仪(大连)科技有限公司 2022-07-29 CN disclosed
EP-3798252-B1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-20210095079-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-04-01 US disclosed
EP-3798252-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2021-03-31 EP disclosed
US-5011891-A Ethylene-alpha olefin copolymers blended with two other plastics EXXON RESEARCH & ENGINEERING COMPANY (US) 1991-04-30 US disclosed
US-4978720-A Two-stage addition polymerization in a tubular reactor using a coordination catalyst to form segmented polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-12-18 US disclosed
US-4843129-A ETHYLENE COPOLYMER OF NARROW MOLECULAR WEIGHT DISTRIBUTION EXXON RESEARCH & ENGINEERING COMPANY (US) 1989-06-27 US disclosed
EP-0258418-A4 ELASTOMER-PLASTIC BLENDS. EXXON RESEARCH ENGINEERING CO (US) 1989-06-26 EP disclosed
EP-0258418-A1 ELASTOMER-PLASTIC BLENDS ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1988-03-09 EP disclosed
EP-0240638-A2 Olefinic chlorosilane and olefinic halide functional group containing polymers and method of forming the same EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-10-14 EP disclosed
WO-1987005312-A1 ELASTOMER-PLASTIC BLENDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-09-11 WO disclosed
WO-1987003606-A1 OLEFINIC CHLOROSILANE AND OLEFINIC HALIDE FUNCTIONAL GROUP CONTAINING POLYMERS AND METHOD OF FORMING THE SAME EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product OR10J3, ALKBH1, ALKBH2 TSHR 4579/4885ALDH1A1 197/4885FAAH 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.