Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395488 | 0.89 | DHFR (0.42) | HSPA5DHFRALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL2140622 | 0.84 | NOS3 (0.38) | DHFRCYP1A2SLC6A2SLC6A4NOS3 | |
| SCHEMBL7941023 | 0.77 | DHFR (0.37) | HSPA5DHFRALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL18951028 | 0.76 | HSPA5 (0.37) | HSPA5DHFRALDH1A1CYP1A2ALOX15 | |
| SCHEMBL21052048 | 0.74 | CYP3A4 (0.39) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL31676788 | 0.74 | CYP3A4 (0.39) | SLC6A2SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL2776269 | 0.74 | CYP3A4 (0.39) | HSPA5ALDH1A1CYP1A2ALOX15CASP7 | |
| SCHEMBL11803532 | 0.73 | HTT (0.42) | HSPA5DHFRALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL10824494 | 0.73 | HTT (0.47) | HSPA5DHFRALDH1A1CYP1A2ALOX15 | |
| SCHEMBL11438351 | 0.72 | HSPA5 (0.35) | HSPA5DHFRALDH1A1CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318450-B1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LTD (GB) | 2014-02-26 | — | — | EP | disclosed |
| US-8461275-B2 | Curing agents and process for their manufacture | Hexcal Composites Limited (GB) | 2013-06-11 | — | — | US | disclosed |
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Corporation Ltd (GB) | 2011-06-02 | — | — | US | disclosed |
| EP-2318450-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | Hexcel Composites Limited (GB) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010018392-A2 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | HEXCEL COMPOSITES LIMITED (GB) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130525-A1 | NOVEL CURING AGENTS AND PROCESS FOR THEIR MANUFACTURE | ARCN1, PUF60, RCOR1 | HSPA5 1961/4885DHFR 1146/4885ALDH1A1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.