Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395488 | 0.87 | DHFR (0.42) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL27726732 | 0.87 | BACE1 (0.39) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL28722459 | 0.78 | BACE1 (0.50) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL2140622 | 0.77 | NOS3 (0.38) | DHFRMEN1GAAKMT2ANOS3 | |
| SCHEMBL1829607 | 0.77 | HSPA5 (0.40) | DHFRMEN1GAAKMT2AHSPA5 | |
| SCHEMBL11803532 | 0.76 | HTT (0.42) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL11438351 | 0.75 | HSPA5 (0.35) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL27792504 | 0.75 | BACE1 (0.35) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL1760666 | 0.74 | DHFR (0.44) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL18951028 | 0.74 | HSPA5 (0.37) | DHFRBACE1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489418-B1 | Novel multicomponent fluid separation membranes | AIR LIQUIDE (FR) | 2001-03-14 | — | — | EP | disclosed |
| EP-0489418-A1 | Novel multicomponent fluid separation membranes | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 1992-06-10 | — | — | EP | disclosed |
| US-5085676-A | Porous polymeric substrate and polyamide separating layer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-04 | — | — | US | disclosed |