Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207674 | 0.93 | F2 (0.40) | FURINOPRM1OPRD1OPRK1PRSS1 | |
| SCHEMBL18282372 | 0.91 | PRMT1 (0.43) | FURINOPRM1OPRD1OPRK1PRSS1 | |
| SCHEMBL18296413 | 0.91 | PRMT1 (0.43) | FURINOPRM1OPRD1OPRK1PRSS1 | |
| SCHEMBL18296764 | 0.90 | PRSS1 (0.57) | OPRM1PRSS1TMPRSS2PRMT1F2 | |
| SCHEMBL16808323 | 0.85 | OPRM1 (0.42) | OPRM1OPRD1OPRK1PRSS1TMPRSS2 | |
| SCHEMBL16808326 | 0.85 | PRMT1 (0.40) | FURINOPRM1OPRD1OPRK1PRSS1 | |
| SCHEMBL22120216 | 0.84 | PRMT1 (0.58) | OPRM1PRSS1TMPRSS2PRMT1F2 | |
| SCHEMBL16808183 | 0.82 | PRMT1 (0.43) | OPRM1OPRD1OPRK1PRSS1TMPRSS2 | |
| SCHEMBL20036303 | 0.82 | LSS (0.36) | FURINOPRM1OPRD1OPRK1PRSS1 | |
| SCHEMBL12461767 | 0.81 | PRSS1 (0.47) | FURINOPRM1PRSS1TMPRSS2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2018-05-31 | — | — | US | disclosed |
| EP-3305759-A1 | GUANIDINE COMPOUND AND BACTERICIDE | Nippon Soda Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016195077-A1 | GUANIDINE COMPOUND AND BACTERICIDE | 日本曹達株式会社 | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180146677-A1 | GUANICIDE COMPOUND AND FUNGICIDE | GUCY1A2, GUCY1B2, GUCY1A1 | FURIN 2530/4885OPRM1 3568/4885OPRD1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.