Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18296396 | 0.82 | FURIN (0.44) | OPRM1OPRD1OPRK1FURINPRSS1 | |
| SCHEMBL20207674 | 0.81 | F2 (0.40) | OPRM1OPRD1OPRK1FURINPRSS1 | |
| SCHEMBL18282372 | 0.79 | PRMT1 (0.43) | OPRM1OPRD1OPRK1FURINPRSS1 | |
| SCHEMBL18296413 | 0.79 | PRMT1 (0.43) | OPRM1OPRD1OPRK1FURINPRSS1 | |
| SCHEMBL18296764 | 0.75 | PRSS1 (0.57) | OPRM1PRSS1F2ST14PRMT1 | |
| SCHEMBL16808323 | 0.74 | OPRM1 (0.42) | OPRM1OPRD1OPRK1PRSS1F2 | |
| SCHEMBL16808326 | 0.73 | PRMT1 (0.40) | OPRM1OPRD1OPRK1FURINPRSS1 | |
| SCHEMBL16808183 | 0.72 | PRMT1 (0.43) | OPRM1OPRD1OPRK1PRSS1F2 | |
| SCHEMBL22120216 | 0.71 | PRMT1 (0.58) | OPRM1PRSS1F2ST14PRMT1 | |
| SCHEMBL20036284 | 0.70 | PRMT1 (0.41) | OPRM1OPRD1OPRK1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305759-A1 | GUANIDINE COMPOUND AND BACTERICIDE | Nippon Soda Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |