Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831013 | 0.82 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL1829702 | 0.76 | TP53 (0.37) | TP53TSHRELANEGABRA1GABRB2 | |
| SCHEMBL1829639 | 0.76 | TP53 (0.37) | TP53TSHRELANEGABRA1GABRB2 | |
| SCHEMBL5201451 | 0.76 | PIK3CA (0.31) | — | |
| Hydrochloric Acid SCHEMBL1828417 | 0.74 | GRM2 (0.41) | TP53TSHRELANE | |
| SCHEMBL27711676 | 0.73 | — | — | |
| SCHEMBL1830214 | 0.69 | TYR (0.50) | TP53TSHR | |
| SCHEMBL5862945 | 0.69 | AHR (0.40) | ELANE | |
| SCHEMBL3272345 | 0.68 | TSHR (0.45) | TP53TSHRELANEGABRA1GABRB2 | |
| SCHEMBL1829709 | 0.68 | GRM2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318375-A1 | IMIDAZOLE CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010009062-A1 | IMIDAZOLE CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2010-01-21 | — | — | WO | disclosed |