Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831013 | 0.77 | GABRA1 (0.31) | — | |
| SCHEMBL9806449 | 0.77 | SELL (0.37) | — | |
| SCHEMBL1829987 | 0.76 | TP53 (0.37) | — | |
| SCHEMBL5199656 | 0.76 | MEP1B (0.35) | — | |
| SCHEMBL21822886 | 0.74 | CTSS (0.35) | — | |
| SCHEMBL5198633 | 0.72 | ERN1 (0.34) | — | |
| SCHEMBL1829471 | 0.72 | ERN1 (0.34) | — | |
| SCHEMBL5200338 | 0.72 | TYR (0.49) | — | |
| SCHEMBL5198649 | 0.72 | CYP3A4 (0.37) | — | |
| SCHEMBL2316538 | 0.71 | MEN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817300-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006057860-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |