Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585101 | 1.00 | CYP2A6 (0.49) | CYP2A6KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL982856 | 0.78 | TSHR (0.46) | KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9012682 | 0.78 | TSHR (0.46) | KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7339250 | 0.78 | TSHR (0.46) | KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9377126 | 0.78 | MAOB (0.52) | CYP2A6KDM4ECYP3A4THRBTSHR | |
| SCHEMBL10902090 | 0.76 | CYP11B2 (0.50) | CYP2A6CYP3A4CHRNB2CHRNA4CYP11B2 | |
| SCHEMBL4453374 | 0.74 | CYP11B2 (0.44) | CYP2A6KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL5021231 | 0.73 | CHRNB2 (0.46) | CYP2A6KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL10243298 | 0.73 | CHRNB2 (0.46) | CYP2A6KDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL28978626 | 0.72 | MAOB (0.41) | KDM4ETSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340525-A | Method for producing and processing synthetic nicotine | 陕西雷曼生物科技有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-113121496-A | Method for preparing bioactive (S) - (-) -nicotine | 刘双红 | 2021-07-16 | — | — | CN | claimed |
| US-20240245099-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | PHILIP MORRIS PRODUCTS S.A. (CH) | 2024-07-25 | — | — | US | disclosed |
| EP-4340648-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | Philip Morris Products S.A. (CH) | 2024-03-27 | — | — | EP | disclosed |
| CN-114276204-B | Preparation method of (S) - (-) -nicotine | 大庆雾泰化工科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117295412-A | Aerosol-generating article with biomarker sensor | 菲利普莫里斯生产公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022243270-A1 | MOUTHPIECE WITH CAPILLARY CHANNEL FOR AN AEROSOL-GENERATING DEVICE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2022-11-24 | — | — | WO | disclosed |
| WO-2022243271-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | PHILIP MORRIS PRODUCTS S.A. (CH) | 2022-11-24 | — | — | WO | disclosed |
| CN-115340525-A | Method for producing and processing synthetic nicotine | 陕西雷曼生物科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114276204-A | Preparation method of (S) - (-) -nicotine | 大庆雾泰化工科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113121496-A | Method for preparing bioactive (S) - (-) -nicotine | 刘双红 | 2021-07-16 | — | — | CN | disclosed |
| CN-107666836-B | Biological control in electronic smoking articles | 菲利普莫里斯生产公司 | 2021-06-08 | — | — | CN | disclosed |
| US-10687556-B2 | Biological control in electronic smoking articles | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-06-23 | — | — | US | disclosed |
| CN-110256403-B | Method for preparing artificial synthetic nicotine | 深圳市馨艺坊生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |
| EP-3307362-B1 | BIOLOGICAL CONTROL IN ELECTRONIC SMOKING ARTICLES | PHILIP MORRIS PRODUCTS SA (CH) | 2020-02-19 | — | — | EP | disclosed |
| US-20180140016-A1 | BIOLOGICAL CONTROL IN ELECTRONIC SMOKING ARTICLES | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-05-24 | — | — | US | disclosed |
| EP-3307362-A1 | BIOLOGICAL CONTROL IN ELECTRONIC SMOKING ARTICLES | Philip Morris Products S.a.s. (CH) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016199062-A1 | BIOLOGICAL CONTROL IN ELECTRONIC SMOKING ARTICLES | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-12-15 | — | — | WO | disclosed |