Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890710 | 0.80 | FFAR1 (0.43) | PTGS2MYCKMT2AMEN1ALDH1A1 | |
| SCHEMBL2394862 | 0.80 | DPP4 (0.58) | PKMKMT2ADPP4APAF1TDP2 | |
| SCHEMBL9890720 | 0.80 | PKM (0.47) | PTGS2PKMKMT2ADPP4MEN1 | |
| SCHEMBL2952259 | 0.77 | P2RX7 (0.47) | PKMP2RX7KMT2AMEN1HSD17B10 | |
| SCHEMBL18302006 | 0.77 | ADRA2A (0.44) | PTGS2MYCS1PR4P2RX7KMT2A | |
| SCHEMBL9890745 | 0.77 | CHRM1 (0.43) | PTGS2PKMP2RX7KMT2ADPP4 | |
| SCHEMBL21590178 | 0.76 | MYC (0.57) | MYCTSHRKMT2AMEN1HSD17B10 | |
| SCHEMBL1091961 | 0.76 | PKM (0.64) | PKMKMT2ASHBGAPAF1TDP2 | |
| SCHEMBL158861 | 0.76 | CTBP2 (0.55) | PTGS2KMT2AMEN1SHBGALDH1A1 | |
| SCHEMBL29718576 | 0.76 | CTBP2 (0.55) | PTGS2KMT2AMEN1SHBGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307715-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198374-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-15 | — | — | WO | disclosed |